Gastrin: Comprehensive Research Guide

Overview

Gastrin is a peptide hormone produced by G cells in the stomach and duodenum. It plays a crucial role in regulating gastric acid secretion and gastric motility, essential for proper digestion.

Mechanism of Action

Gastric Function

• **Acid Secretion': Stimulates gastric acid production
• **Gastric Motility': Enhances gastric motility
• **Mucosal Growth': Promotes gastric mucosal growth
• **Digestion': Supports digestive processes

Regulation

• **Food Intake': Released in response to food
• **Neural Control': Regulated by neural inputs
• **Feedback': Subject to negative feedback

Research Applications

Digestive Research

• **Gastric Function': Research into gastric function
• **Peptic Ulcers': Research into peptic ulcer disease
• **GI Disorders': Research into GI conditions

Medical Applications

• **Diagnostic': Used in diagnostic tests
• **Gastrinomas': Research into gastrin-secreting tumors

Dosage

• **Research': Dose-dependent, protocols vary
• **Administration': Intravenous or subcutaneous
• **Half-Life': Short half-life (5-10 minutes)

Side Effects

• **GI Effects': Possible GI effects
• **Acid Secretion': Increases acid secretion

This information is for research and educational purposes only.