hormonalMolecular Weight: 1269.4

Goserelin

Zoladex

An LHRH agonist used to treat breast cancer, prostate cancer, and endometriosis. Suppresses hormone production.

Mechanism

LHRH agonist that suppresses gonadotropin release. Used to treat hormone-sensitive cancers and endometriosis.

Half-Life

4-5 hours

Administration

Subcutaneous

Technical Protocol

Goserelin: Comprehensive Research Guide

Overview

Goserelin (Zoladex) is a synthetic LHRH agonist used to treat hormone-sensitive cancers and endometriosis. It works by suppressing gonadotropin release, leading to reduced hormone production.

Mechanism of Action

**Hormone Suppression': Suppresses LH and FSH release
**Hormone Reduction': Reduces testosterone and estrogen
**Tumor Control': Controls hormone-sensitive tumors

Research Applications

Medical Applications

**Breast Cancer': Treatment of hormone-sensitive breast cancer
**Prostate Cancer': Treatment of prostate cancer
**Endometriosis': Treatment of endometriosis

Dosage

**Standard': 3.6 mg monthly or 10.8 mg every 3 months
**Administration': Subcutaneous implant
**Duration': Varies by condition

Side Effects

**Hot Flashes': Common hot flashes
**Libido': Decreased libido
**Mood Changes': Possible mood changes

This information is for research and educational purposes only. Goserelin is a prescription medication.

Peer-Reviewed Citations

Goserelin in the treatment of breast cancer

Kaufmann M, et al. • N Engl J Med (2003)

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Frequently Asked Questions

What is Goserelin?

An LHRH agonist used to treat breast cancer, prostate cancer, and endometriosis. Suppresses hormone production.

How does Goserelin work?

LHRH agonist that suppresses gonadotropin release. Used to treat hormone-sensitive cancers and endometriosis.

What is the typical dosage of Goserelin in research?

The typical research dosage of Goserelin is 3.6 mg (range: 3.6-10.8 mg). Common administration routes include Subcutaneous.

How should Goserelin be stored?

Store at room temperature

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