Semaglutide
Ozempic • Wegovy
Mechanism
GLP-1 receptor agonist. Increases insulin secretion, decreases glucagon, and slows gastric emptying.
Half-Life
7 days
Administration
Technical Protocol
Semaglutide: Comprehensive Research Guide
Overview
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved for type 2 diabetes (Ozempic) and chronic weight management (Wegovy). With a half-life of approximately 7 days, it allows for once-weekly administration.
Mechanism of Action
- Binds to GLP-1 receptors
- Stimulates insulin secretion
- Suppresses glucagon
- Slows gastric emptying
- Reduces appetite
This information is for research and educational purposes only.
Peer-Reviewed Citations
Once-weekly semaglutide in adults with overweight or obesity
Wilding JPH, et al. • N Engl J Med (2021)
Access ResearchFrequently Asked Questions
What is Semaglutide?
A widely used GLP-1 analog for type 2 diabetes and chronic weight management.
How does Semaglutide work?
GLP-1 receptor agonist. Increases insulin secretion, decreases glucagon, and slows gastric emptying.
What is the typical dosage of Semaglutide in research?
The typical research dosage of Semaglutide is 1 mg weekly (range: 0.25-2.4 mg weekly). Common administration routes include Subcutaneous.
How should Semaglutide be stored?
Store at 2-8°C, protect from light
Source Semaglutide for Your Research
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