Fragment 176-191: Comprehensive Research Guide

Overview

Fragment 176-191 (also known as HGH Frag 176-191 or AOD-9604 Fragment) is a 16-amino acid peptide derived from the C-terminal region of human growth hormone (amino acids 176-191). This fragment has been studied for its selective fat-burning properties without the systemic effects of full HGH.

Mechanism of Action

Selective Fat Metabolism

• Lipolysis: Promotes breakdown of stored fat (triglycerides)
• Fat Cell Targeting: Specifically targets adipocytes (fat cells)
• No Growth Effects: Does not stimulate growth hormone receptors
• Metabolic Enhancement: Increases metabolic rate in fat tissue

Key Differences from HGH

• No Blood Sugar Impact: Does not affect glucose metabolism
• No Growth Stimulation: Does not promote muscle or bone growth
• Targeted Action: Primarily affects fat cells
• Shorter Half-Life: Rapid clearance from system

Research Applications

Fat Loss Research

• Targeted Fat Reduction: May reduce stubborn fat deposits
• Metabolic Rate: Increases fat metabolism
• Body Composition: Improves body fat percentage
• Spot Reduction: Potential for localized fat reduction

Comparison to AOD-9604

• Similar Structure: Related to AOD-9604
• Different Effects: May have distinct mechanisms
• Research Status: Both under investigation

Dosage Protocols

Standard Protocol

• Dose: 200-500 mcg daily
• Typical: 300 mcg twice daily
• Timing: Morning and evening
• Administration: Subcutaneous injection

Cycle Recommendations

• Duration: 8-12 weeks
• Cycles: 8 weeks on, 4 weeks off
• Stacking: Often combined with other peptides

Side Effects

• Minimal: Generally well-tolerated
• Injection Site: Mild irritation possible
• No Hormonal: Does not affect hormone levels
• No Blood Sugar: Safe for diabetics

Storage

• Temperature: 2-8°C (refrigerated)
• Light: Protect from light
• Reconstituted: Stable for 2-3 weeks refrigerated

This information is for research and educational purposes only.