Matrixyl
Palmitoyl Pentapeptide-4
Mechanism
Cosmetic peptide that stimulates collagen production and extracellular matrix synthesis. Promotes skin repair and reduces appearance of wrinkles.
Half-Life
Topical
Administration
Technical Protocol
Matrixyl: Comprehensive Research Guide
Overview
Matrixyl (Palmitoyl Pentapeptide-4) is a synthetic peptide widely used in anti-aging skincare products. It stimulates collagen production and extracellular matrix synthesis, leading to improved skin texture, firmness, and reduced appearance of wrinkles.
Mechanism of Action
Collagen Stimulation
- Collagen Synthesis: Increases production of collagen types I, III, and IV
- Extracellular Matrix: Enhances matrix protein synthesis
- Fibroblast Activity: Stimulates fibroblast proliferation
- Skin Repair: Promotes skin tissue repair
Cosmetic Benefits
- Wrinkle Reduction: Diminishes depth and appearance of wrinkles
- Skin Firmness: Improves skin elasticity and firmness
- Texture: Enhances skin texture and smoothness
- Hydration: May improve skin hydration
Research Applications
Skincare
- Anti-Aging: Reduces signs of aging
- Wrinkle Treatment: Topical wrinkle reduction
- Skin Repair: Promotes skin healing
- Cosmetic Formulations: Used in serums, creams, and lotions
Dosage
- Topical: 3-5% solution in cosmetic formulations
- Application: Twice daily to affected areas
- Duration: Results visible after 4-8 weeks
Side Effects
- Minimal: Generally well-tolerated
- Skin Irritation: Possible mild irritation
- Allergic: Rare allergic reactions
This information is for research and educational purposes only.
Peer-Reviewed Citations
Palmitoyl pentapeptide-4 (Matrixyl) stimulates collagen synthesis
Lintner K, et al. • J Cosmet Dermatol (2002)
Access ResearchFrequently Asked Questions
What is Matrixyl?
One of the most popular cosmetic peptides, Matrixyl stimulates collagen production and improves skin texture and firmness.
How does Matrixyl work?
Cosmetic peptide that stimulates collagen production and extracellular matrix synthesis. Promotes skin repair and reduces appearance of wrinkles.
What is the typical dosage of Matrixyl in research?
The typical research dosage of Matrixyl is 3-5% solution (range: Topical application). Common administration routes include Topical.
How should Matrixyl be stored?
Store at room temperature, protect from light
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