Neuropeptide Y: Comprehensive Research Guide

Overview

Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that is one of the most abundant peptides in the central nervous system. It plays crucial roles in appetite regulation, stress responses, energy balance, and various physiological processes.

Mechanism of Action

Appetite Regulation

• **Appetite Stimulation': Increases food intake
• **Energy Balance': Regulates energy balance
• **Obesity': Involved in obesity mechanisms
• **Receptor Binding': Binds to Y1, Y2, Y4, Y5 receptors

Stress & Mood

• **Stress Response': Modulates stress responses
• **Anxiety': Involved in anxiety regulation
• **Mood': Plays roles in mood regulation
• **Coping': May influence stress coping

Research Applications

Obesity Research

• **Appetite Control': Research into appetite regulation
• **Weight Management': Research into weight control
• **Metabolic Disorders': Research into metabolic conditions
• **Food Intake': Research into food intake mechanisms

Stress Research

• **Stress Management': Research into stress responses
• **Anxiety': Research into anxiety disorders
• **Mood Disorders': Research into mood conditions

Dosage

• **Research': Dose-dependent, protocols vary
• **Administration': Intracerebroventricular or intranasal
• **Frequency': Varies by research protocol

Side Effects

• **Appetite': Increases appetite (expected effect)
• **Hypotension': Possible low blood pressure
• **Mood': May affect mood

Storage

• **Temperature': -20°C (frozen)
• **Light': Protect from light
• **Stability': Requires careful storage

This information is for research and educational purposes only.