Adipotide: Comprehensive Research Guide

Overview

Adipotide (FTPP, Prohibitin-Targeting Peptide) is an experimental peptide designed to selectively target and destroy fat cells. It works by binding to prohibitin, a protein found on blood vessels that supply white adipose tissue, causing apoptosis (programmed cell death) of fat cells.

Mechanism of Action

Fat Cell Targeting

• Prohibitin Binding: Binds to prohibitin on fat tissue blood vessels
• Apoptosis: Causes programmed cell death of fat cells
• Selective: Targets white adipose tissue specifically
• Irreversible: Fat cell destruction is permanent

Research Status

• Experimental: Early-stage research
• Preclinical: Animal studies completed
• Human Trials: Limited human research
• Safety: Significant safety concerns identified

Research Applications

Weight Loss Research

• Fat Reduction: Significant fat loss in animal models
• Targeted: Selective fat cell destruction
• Obesity: Research into obesity treatment
• Stubborn Fat: Potential for resistant fat deposits

Safety Concerns

• Kidney Toxicity: Kidney damage reported in studies
• Side Effects: Significant side effects observed
• Research Only: Not approved for human use
• Caution: Requires careful research protocols

Dosage

• Research: 0.5-2.0 mg/kg body weight
• Frequency: Daily or every other day
• Duration: Limited duration protocols
• Monitoring: Requires medical monitoring

Side Effects

• Kidney Toxicity: Kidney damage and dysfunction
• Injection Site: Reactions at injection site
• Fatigue: Significant fatigue reported
• Dehydration: Increased risk of dehydration

Warnings

• Experimental: Research use only
• Safety: Significant safety concerns
• Medical Supervision: Requires medical supervision
• Not Approved: Not approved for human use

This information is for research and educational purposes only. Adipotide is experimental and not approved for human use.