Glutathione: Comprehensive Research Guide

Overview

Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine. It is the body's most important antioxidant and plays a crucial role in detoxification, immune function, and cellular health. Often called the "master antioxidant."

Mechanism of Action

Antioxidant Function

• Free Radical Scavenging: Neutralizes harmful free radicals
• Oxidative Stress: Protects cells from oxidative damage
• Regeneration: Regenerates other antioxidants (vitamin C, E)
• Cellular Protection: Protects DNA, proteins, and lipids

Detoxification

• Liver Function: Essential for liver detoxification
• Toxin Removal: Binds and removes toxins
• Heavy Metals: Chelates heavy metals
• Drug Metabolism: Involved in drug metabolism

Immune Function

• Immune Support: Supports immune system function
• Lymphocyte Function: Enhances lymphocyte activity
• Antioxidant Defense: Protects immune cells

Research Applications

Health & Longevity

• Anti-Aging: May slow aging process
• Detoxification: Supports detoxification
• Immune Health: Enhances immune function
• Skin Health: Promotes skin health and lightening

Medical Applications

• Liver Disease: Research into liver conditions
• Cancer: Research into cancer prevention
• Neurodegenerative: Research into brain health
• Cardiovascular: Research into heart health

Dosage

• IV: 200-1000 mg (medical setting)
• Subcutaneous: 50-200 mg
• Oral: 100-500 mg (lower bioavailability)
• Topical: For skin lightening applications

Side Effects

• Minimal: Generally well-tolerated
• Allergic: Rare allergic reactions
• IV: Possible reactions with IV administration

Storage

• Temperature: 2-8°C (refrigerated)
• Light: Protect from light
• Stability: Relatively stable when properly stored

This information is for research and educational purposes only.